Is ‘the worst cold ever’ going around?

Woman sneezing into a tissue

BBC- You’ve probably heard a lot more sniffles around if you’ve gone out recently or got on public transport.

Perhaps there’s that one person on the work call who’s not muted and starts a coughing fit before a meek: “It’s not Covid, I’ve been tested!”

Or, maybe you’ve been ill and agree with people saying that what’s going around right now is “the worst cold ever.”

Well get used to it. Because cold season has begun.

And some people are already suffering.

‘Nothing like this’

One of those is 24-year-old Rebecca London.

The retail worker from Bournemouth caught what she calls “the worst cold ever” at a festival.

Rebecca
It’s the “worst cold” Rebecca has had

A normal cold for her would have “a runny nose, sneezing, a bit of a sore throat and feeling a bit rundown”.

“Nothing like this,” she tells Radio 1 Newsbeat.

“I barely slept, I’d wake up in the night just coughing, a constantly runny nose and feeling so tired,” she adds.

Rebecca did lateral flow tests and got negative results, but has been ill for more than a week, and was left wondering “if it’s ever going to end”.

And she’s not the only one.

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It may not be Covid, but it is linked to what’s happened in the past 18 months.

“We’ve actually been seeing a rise in the number of coughs and colds and viral infections,” says Dr Philippa Kaye, a GP based in London.

She says the numbers have been as high as you’d see in a normal winter and the main reason is because of the easing of coronavirus restrictions.

“We are mixing in a way that we haven’t been mixing over the past 18 months,” says Dr Philippa.

“During those first lockdowns, we saw numbers of other [non-Covid] infections fall. We think that that was primarily due to the restrictions on meeting up.”

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The BBC is not responsible for the content of external sites.View original tweet on Twitter
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So while the lockdown rules were designed to stop Covid spreading, they also stopped other viruses moving between people too.

Now we’re going out, meeting with friends and getting on public transport again, the common cold spreads again.

“Most of these things are respiratory driven, so say somebody talks or coughs or sneezes – you breathe it in,” says Dr Philippa.

What do I do about it?

Firstly, remember the three main symptoms of coronavirus. If you have one of these, get a PCR test.

  • New and continuous cough – coughing a lot for more than an hour, or having three or more coughing episodes in 24 hours
  • Fever – a temperature above 37.8C
  • Change in smell or taste – either you cannot taste or smell anything, or these senses are different to normal.

If you don’t have these symptoms but still want to check, you can do a free lateral flow test in England and Scotland. In Wales and Northern Ireland, certain people are eligible.

“Let’s say that you’ve got a cough or cold and it is not coronavirus. Then most of the time these can be managed at home,” says Dr Philippa.

Her recommendation is to have “loads of fluids and rest, over-the-counter simple painkillers for headaches and aches and pains.

“Even simple things like honey in a hot drink can help ease a sore throat.”

 

She adds: “You can get lots of advice from your local pharmacist for minor coughs and colds.

“But if you become more unwell, if you cough up blood, have chest pain, if you have shortness of breath or chest tightness, then you need to seek medical advice.”

Freshers flu

Look, we don’t want to put new university students off their exciting first few weeks but freshers’ flu will be pretty much unavoidable.

Just ask 18-year-old Noor Hashmi – studying at the University of Edinburgh, she’s suffering with the worst illness she’s ever had.

“Normally I’m still able to go about my day, but this one left me with muscle fatigue, a lost voice and headache that meant I’ve just stayed indoors.”

Noor
Noor has taken both a lateral flow and PCR test to rule out Covid because her symptoms were getting so bad

It’s not actually flu though – it’s just another version of the common cold.

Add in the fact that students’ immune systems will probably take a battering from going out a lot, and you’ll be vulnerable to it.

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Luckily, protecting yourself isn’t rocket science – it’s a case of eating well, getting enough sleep and washing your hands regularly.

And remember to register for your local GP if you’re moving somewhere new.

Noor can’t wait to get back to socialising properly.

“Although I think it’ll be some time before I’m socialising in a large group because everyone seems to have freshers flu right now,” she adds.

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Covid: Immune therapy from llamas shows promise

By Victoria Gill
Science correspondent, BBC News

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Fifi the 'Franklin llama' lives at a farm facility at the University of Reading
Fifi the ‘Franklin llama’ lives at a farm facility at the University of Reading

A Covid therapy derived from a llama named Fifi has shown “significant potential” in early trials.

It is a treatment made of “nanobodies”, small, simpler versions of antibodies, which llamas and camels produce naturally in response to infection.

Once the therapy has been tested in humans, scientists say, it could be given as a simple nasal spray – to treat and even prevent early infection.

Prof James Naismith described nanobodies as “fantastically exciting”.

Llamas (c) University of Readingimage source, University of Reading
image captionLlamas, alpacas, camels and sharks have evolved to produce nanobodies in response to infection

Prof Naismith, who is one of the lead researchers and director of the Rosalind Franklin Institute in Oxfordshire, explained that coronavirus-infected rodents treated with the new nanobody nasal spray fully recovered within six days.

The treatment has, so far, been tested only in those lab animals, but Public Health England said it was among the “most effective SARS-CoV-2 neutralising agents” it had ever tested.

This apparent covid-fighting potency comes from the strength with which nanobodies bind to the virus.

Just like our own antibodies, virus-specific nanobodies latch on to and bind to viruses and bacteria that invade our bodies. This binding essentially tags an invading virus with an immune “red flag”, to allow the rest of the body’s immune armoury to target it for destruction.

The nanobodies that these researchers produced – with the help of a llama’s immune system – bind particularly tightly.

“That’s where we had some help from Fifi the ‘Franklin [Institute] llama’,” explained Prof Naismith.

By vaccinating Fifi with a tiny, non-infectious piece of the viral protein, the scientists stimulated her immune system to make the special molecules. The scientists then carefully picked out and purified the most potent nanobodies in a sample of Fifi’s blood; those that matched the viral protein most closely, like the key that best fits a specific lock.

The team was then able to grow large quantities of the specially selected, most potent molecules.

How the process works
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Prof Naismith told BBC News: “The immune system is so marvellous that it still does better than we can – evolution is hard to beat.”

Llamaimage source, Getty Images

Professor Sheena Cruickshank, an immunologist from the University of Manchester said the new development was “exciting but still quite early”.

“We need more data on efficacy and safety before we move to human trials,” she added. “However it’s very promising nonetheless and the fact it may be cheaper and easier to administer is a plus. Covid-19 will be, unfortunately, with us for a while yet, so more treatments will be needed.”

Professor Naismith and his collaborators, who published their research in the journal Nature Communications agreed that, even with the success of the Covid vaccines, having effective treatments in the future would be very important.

“Not all of the world is being vaccinated at the same speed,” he said, “and there remains a risk of new variants capable of bypassing vaccine immunity emerging.”

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Compiled by Karishma Singh Editing by Robert Birsel